Super Metroid: Mother Brain Pokémon Platinum: Cynthia Mario 64: Bowser Fight Legend of Zelda OoT: Ganondorf Kirby's Return to Dreamland: Magalor Bioshock Series: Big Daddies/ Sisters (Bouncer, Rosie, Rumbler, Lancer, etc.) Shadow of the Colossus: Colossi Sonic Generations: Perfect Chaos Punch-Out (Wii): Donkey Kong Super Smash Bros. Melee: Giga Bowser And those are just to name some of them...